A:
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Don't use emulatorx, i guess it is not working well.
A cosmetically-acceptable cream or lotion having a dermatologically-active component, e.g., a corticosteroid such as a hydrocortisone ester, is well known in the art. These compounds have proven to be very beneficial in the treatment of, e.g., dermatitis and/or eczema, and many have even been included as pharmaceutical products in over-the-counter (OTC) formulations.
These OTC formulations may be used for a variety of dermatologic conditions, including, e.g., those with exudative symptoms such as dermatitis, eczema, and psoriasis. In some of these cases, the patient's skin may be moistened prior to application of the OTC formulation to the skin. Other OTC formulations may be applied to dry skin and/or to dry skin that has been moisturized.
In both of these cases, there is a need to deliver the dermatologically-active component to the affected skin in an efficacious manner, in a manner which will prevent the dermatologically-active component from leaking into the skin or from the skin being so absorbed that the active ingredient is lost.
The dermatologically-active components may be applied as cream or lotion to affected areas of the skin. Oils that have been used in the prior art to form the dermatologically-active component in a composition may have certain drawbacks. In particular, oil-based dermatologically-active components may be difficult to apply to dry skin without a separate moisturizer and/or may be slow to dry the skin.
It has now been found that certain esters of glycerin and hydrocortisone can be applied to the skin in a composition having a dermatologically-active component while maintaining the desired properties. In particular, esters of hydrocortisone can be used in compositions comprising an active ingredient to deliver the active ingredient to the skin in a highly efficient manner.
The use of esters of hydrocortisone, such as glyceryl, is be359ba680
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